PRECISION MEDICINE
PATENTED IMMUNOLOGY EXTRACTION TECHNOLOGY
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G’NEST is a scientifically-validated immuno-organic compound that carefully regulates and balances the immune system in our body to deter auto-immune diseases.
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IP application number : 10201802979V
7 Scientific Discoveries of G'Nest
1
ENHANCE IMMUNITY AGAINST INFECTION
Restrict dengue viruses replication upon direct application to macrophages (immune cells in human beings) cell culture.
Discovery in anti-dengue viral effects could cause the production of inflammatory cytokines (including IFN-β) in macrophages.
2
BETTER MANAGEMENT OF CHRONIC DISEASES
This discovery as an immunological concentrate could induce B-lymphocytes cells (white blood cells) to produce cytokines in culture.
Cytokines stimulate the movement of cells towards sites of inflammation, infection and trauma.
These cytokines could enable us to cope better with the very challenging various chronic diseases such as deadly influenza, diabetes, arthritis, multiple sclerosis, etc.
3
ENHANCE PREVENTION OF INFECTION AND CANCER
Cytokines are “immuno-modulating” molecules that balance and regulates our immune system responses in our body. This “balancing” produce great effects in preventing microbial infections and better management of cancers e.g. breast cancer.
4
SUSTAINABLE B-CELL CYTOKINE PRODUCTION
This discovery as an immunological concentrate could have a dose-dependent effects on B-cells for cytokine production, including sustainable and prolonged effects. By using complement proteins, and a combination of immune peptides that may not be closely associated to B cells, dose dependent effects on B cells for cytokine production may be achieved.
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5
BETTER MANAGEMENT OF CANCER AND INFLUENZA
The immunological concentrate could induce phosphorylation which activates IRF3. IRF3 (phosphorylated) has been linked with enhanced anti-cancer and anti-viral prevention properties through interaction with IRF7, another signalling molecule. This could potentially be used for post-myocardial infarction cardioprotection (disrupts possible onset of heart failure).
6
REGULATE IMMUNE SYSTEM
As an immunological concentrate, it could induce NF-κB immune regulating pathway. NF-κB plays a key role in regulating the immune response against infection. NF-κB has also been implicated in processes of synaptic plasticity and memory which have been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and defective immune development. The immunological concentrate also induce MAPKs immune regulating pathway, which are involved in regulating cell functions and directing cellular responses to multiple stimulus such as proinflammatory cytokines. DHA or E4 EBN Extracts may be used in the enhanced management of the various forms of stress, heat shock, and septic shock and viral infections.
7
BALANCE INFLAMMATORY FACTORS
As an immunological formulation, this concentrate balances the expression of pro-inflammatory and anti-inflammatory molecules in the brain, and reduces the number of inflammatory cells, thus reducing neuron inflammation and increases the production of nerve growth factor, consequently improving neuronal survival.